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Medications and Therapy For ADHD Combining medication and therapy can help to manage ADHD. The medication treats the brain, while therapy helps people manage and develop skills. Stimulants like methylphenidate or Lisdexamfetamine boost the levels of two chemicals that transmit messages between cells in the brain. This can increase attention, impulse control and motivation. The stimulants can have negative side effects, like difficulty sleeping, loss of appetite, and increased heart rate and bloodpres
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