https://www.selleckchem.com/pr....oducts/spautin-1.htm
Immunotherapy has become a hotspot in cancer therapy in recent years. Several immune checkpoints inhibitors have been used to treat lung cancer. CD137 is a kind of costimulatory molecule that mediates T cell activation, which regulates the activity of immune cells in a variety of physiological and pathological processes. Targeting CD137 or its ligand (CD137L) has been studied aiming to enhance anti-cancer immune responses. Accumulating studies present that anti-CD137 monoclonal antibodies alone or combined with other drugs have bright