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5-101.8, versus 104.4, 95% CI 100.4-108.4, P=0.001, Q0.001 [Q refers to the false discovery rate adjusted P value], and 3.9, 95% CI 3.6-4.3, versus 4.5, 95% CI 4.1-4.9, P=0.005, Q=0.045, respectively). A significant difference in diastolic blood pressure was found, with higher values in chemotherapy-exposed (61.1, 95% CI 59.0 to 63.2) versus control children (56.0, 95% CI 54.1 to 57.8) (P0.001, Q0.001) and in a subgroup of 59 anthracycline-exposed (61.8, 95% CI 59.3 to 64.4) versus control children (55.9, 95% CI 53.6 to 58.1)