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All functional tests except microperimetry showed a significant loss in diabetic patients (P 0.05). Both FDT and microperimetry showed a significant relationship with the GC count (P 0.05), consistent with predictions from a neural model for partial summation conditions. However, the FDT captured additional significant damage (P = 0.03) unexplained by the structural loss. Functional and structural measurements support early neuronal loss in diabetes. The structure-function relationship follows the predictions from an establish
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