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2-butoxyethanol is a widely used organic solvent. The United States Toxic and Disease Registry (ATSDR) listed 2-butoxyethanol as a suspected human carcinogen. In this paper, we reviewed the research progress of methylene chloride metabolism and absorption in vivo, toxicity and biological monitoring in recent years.To project the basis of occupational health examination quality assessment, and put forward advices for cheking the quality and safety of occupational health examination, assessment requirements, the key points on-site, uti