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It is envisaged that the use of multiple loops of suture to anchor mobile tissue onto fixed sturdy fascia will contribute to the longevity of the results. The limited skin undermining also makes this procedure a better choice for smokers. © 2020 Wiley Periodicals, Inc.The mitochondrial calcium uniporter (MCU) is the ion channel that mediates Ca2+ uptake in mitochondria. Inhibitors of the MCU are valuable as potential therapeutic agents and tools to study mitochondrial Ca2+ . The best-known inhibitor of the MCU is the ruthenium compound R