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What Happens If ADHD is Left Untreated in Adults? Untreated ADHD can lead to a myriad of problems for adults. These issues can affect relationships, work and mental health. Adults with untreated ADHD often suffer from low self-esteem, as well as an unfavorable view of the world. They may feel as if they are failures at home and work. Lack of Focus It is normal to experience difficulties focusing from time to moment particularly after a hectic day at school or work. However, if you start to notice that your focus has been becoming more difficult and