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Optoacoustic interaction can be strongly enhanced in tiny core fibers, and it holds significant potential for stable harmonic mode-locking at gigahertz (GHz) and higher repetition rate. In this Letter, we propose and demonstrate a microfiber-assisted GHz harmonic mode-locking fiber laser, which is achieved by the enhanced optomechanical coupling between cavity modes in microfiber with the waist length of ∼16cm and the waist diameter of ∼1.56µm. The repetition rates can be stably locked at 2.3828 GHz and predominately locked at 1.7852 GHz, corresponding to t