https://www.selleckchem.com/pr....oducts/hmpl-504-azd6 
  405 allografts were explanted for structural failure, actuarially 2%, 14%, 34%, and 51% at 5, 10, 15, and 20 years. Risk factors for structural failure were younger recipient age, larger body surface area, hypertension, and thoracic aorta disease; donor factors were older age and larger allograft size. Implant for infective endocarditis was not associated with accelerated structural failure. This study affirms allografts' long-term acceptable hemodynamic performance and durability. Concern about structural failure sho
 
					 
						 
                    
                                     
					 
					 
					 
             
       
       
       
       
       
       
       
       
       
         