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Further, we discuss a new mode of metabolic regulation driven by epigenetic mechanisms, that enables cancer cells to autonomously activate iron metabolism for their survival. Together, these underscore the integration of genetic mutations with metabolic reprogramming and epigenetic shifts in cancer, suggesting a new means to identifying patient subsets suitable for specific precision therapeutics. 2020 The Japan Society of Histochemistry and Cytochemistry.Calcium sulfate is one of the most common inorganic salts with a high scaling potent
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