https://www.selleckchem.com/products/phtpp.html
D447A contributed the most to the enhanced dynamics of the NTD, with reduced calorimetric enthalpy of HK2. Similar residues exist in the C-terminal domain (CTD) but are unnecessary for HK1 and HK2 activity. Thus, we postulate these residues serve as a regulatory site for HK2, and may provide new directions for the design of anticancer therapeutics that reduce the rate of glycolysis in cancer through specific inhibition of HK2.The ClpB/DnaK bi-chaperone system reactivates aggregated cellular proteins and is essential for survival of bacter

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