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We report a 16-year old male, obtained HIV infection vertically, was on second range regimen due to virological failure since 3 years. His current CD4 lymphocyte matter is 835 cells/uL with viral RNA degree of 33,008 copies/mL. Currently given progressive forgetfulness, gait imbalance, and a frequent staring episodes without lack of postural tone. Neurologic evaluation ended up being pertinent for cognitive disorder with rating of 6 on Global HIV Dementia Scale (motor-speed = 3, psycho