https://www.selleckchem.com/pr....oducts/oxidopamine-h
Independent T-test with ANOVA and Tukey's post hoc was done. RESULTS RAGE inhibitors yielded a significant decrease in blood glucose and HbA1c levels. VEGF and RAGE expression were reduced in anti-RAGE groups in various doses. Inhibition of RAGE reduced the damage of retinal pericytes, by reducing GFAP and increasing NGF, and reduced the formation of new blood vessels, by decreasing VEGF expression, in diabetic retinopathy. CONCLUSION Inhibition of receptor for advanced glycation end-products (RAGE) was effective in sup
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