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ADHD in Adults Undiagnosed Undiagnosed ADHD is a difficult condition to manage, and can cause years of shame and low self-esteem. This can lead to depression, mental health issues, and even abuse of substances. In contrast to children, diagnosing ADHD in adults requires a thorough history, which may include a psychological exam and interviewing the person's close family members for their perspectives on childhood behavior. 1. Problems in Focusing People with ADHD have a hard time staying focused. Adult ADHD is also associated with forgetfulness. If