https://www.selleckchem.com/pr....oducts/ly3537982.htm
We discuss the limitations of pain models when research findings fail to be translated from animal models to human clinics. But we also point to some recent successes in analgesic drug development that highlight strategies for improving the predictive validity of animal models of pain. Finally, we emphasize the importance of using assortments of preclinical pain models to identify pain subtype mechanisms, and to foster the development of better analgesics.In plants, hypoxia (low-oxygen stress) is induced by soil waterlogging or submer