https://www.selleckchem.com/pr....oducts/isa-2011b.htm
BACKGROUND A watch-and-wait strategy is a nonoperative alternative to sphincter-preserving surgery for patients with locally advanced rectal cancer who achieve a clinical complete response after neoadjuvant therapy. There are limited data about bowel function for patients undergoing this organ-preservation approach. OBJECTIVE To compare bowel function in patients with rectal cancer managed with a watch-and-wait approach to bowel function in patients who underwent sphincter-preserving surgery (total mesorectal excision). DESIGN Retrosp