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Studies will be selected based on their assessment against the inclusion criteria by two independent reviewers. Eligible studies will be critically appraised for methodological quality. Data will be extracted using a standardized tool and findings pooled and synthesized using a meta-aggregation approach. We are rejecting this submission as we do not consider it to meet the scope of PROSPERO as reviews need to contain at least one outcome of direct patient or clinical relevance in order to be included in PROSPERO. We are rejecting this sub
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