https://www.selleckchem.com/pr....oducts/Tretinoin(Abe
The data demonstrate that SAB attenuated injury-induced IDD and oxidative stress, caused by activation of the JAK2/STAT3 signaling pathway . Oxidative stress induced by H O was reversed by SAB . SAB reduced the increased cell apoptosis, cleaved caspase-3 expression, and caspase-3 activity induced by H O . Reduced cell proliferation and decreased Bcl-2/Bax ratio induced by H O were rescued by SAB. Additionally, the JAK2/STAT3 pathway was activated by SAB, while AG490 counteracted this effect. The results suggest that SAB prote