https://www.selleckchem.com/sc....reening-libraries.ht
This paper addresses the problem of identification of PPV and NPV given knowledge of sensitivity and specificity and given bounds on prevalence. I explain the problem and show how to bound PPV and NPV as well as the risk ratio and difference, which are functions thereof. I apply the findings to COVID-19 antibody tests. I question the realism of supposing that sensitivity and specificity are known. The opioid epidemic continues to be an ongoing public health crisis in the United States. Initially, large increases in overdose death rat