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For individual citrus products, participants with the most orange and orange juice consumption ( 1 serving per day) had a significantly increased melanoma risk relative to those with no consumption (OR 1·79, 95% CI 1·07-2·78 and OR 1·54, 95% CI 1·10-2·10, respectively). Fair- or very fair-skinned participants with high citrus consumption had an even greater melanoma risk (OR 1·75, 95% CI 1·31-2·29). High citrus consumption was associated with an increased risk of melanoma in a large, prospective, population-based cohort. Further val