https://www.selleckchem.com/pr....oducts/Clofarabine.h
Furthermore, we found that human lung CD8+ TRM are composed of two functionally distinct populations based on PD1 and ZNF683 (HOBIT) protein expression. We show that MLR provide co-stimulatory signaling to PD1hi CD4+ and CD8+ lung TRM, augmenting TRM effector cytokine production and degranulation. Ex-vivo lung perfusion provides an innovative technique to study resident immune populations in humans. Human lung resident macrophages co-localize with and provide co-stimulation signaling to tissue resident memory T cells, augmenting the