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Copyright© Bentham Science Publishers; for just about any questions, please email at epub@benthamscience.net.Various nutritional elements were designated as anti-oxidants, with a potential effect on conditions through the loves of cancer tumors. This will be partially for their influence on prostaglandins, thus affecting regional pathological metabolic acidosis. This report aims to review to blame pathophysiological mechanisms involved, with a focus regarding the bone tissue microenvironment. The omega-6/omega-3 PUFA p