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These sunscreen products were also characterized for several formulation properties including the globule size in emulsions, which was found to be an indicator for the rank order. Histone deacetylase inhibitors, including valproic acid, selectively induce cellular differentiation and apoptosis in melanoma cells. No published pharmacoepidemiology studies have explored the association between valproic acid use and melanoma risk. We conducted a retrospective cohort study of adult white Kaiser Permanente Northern California members (n=2,213,845) from 1997-2012