https://www.selleckchem.com/products/en4.html
Combined pituitary hormone deficiency (CPHD) is a genetically heterogeneous disorder caused by mutations in over thirty genes. Loss of function mutations in many of these genes, including Orthodenticle homeobox 2 (OTX2), can present with a broad range of clinical symptoms, which provides a challenge for predicting phenotype from genotype. Another challenge in human genetics is functional evaluation of rare genetic variants that are predicted to be deleterious. Zebrafish are an excellent vertebrate model for evaluating gene function and dise
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