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The obtained results support the recent observation that CK2 inhibitors can improve 5-FU-based anticancer therapy and FAK kinase can be an attractive molecular target in breast cancer therapy. The obtained results support the recent observation that CK2 inhibitors can improve 5-FU-based anticancer therapy and FAK kinase can be an attractive molecular target in breast cancer therapy.Peripheral neuropathy (PN) is a debilitating complication of diabetes that affects 50% of patients. Recent evidence suggests that obesity and metabolic d