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5 IU·mL (treatment). Friedman test with post hoc Dunn-Bonferroni test was used for between-group comparisons. RESULTS Heparin 0.5 IU·mL triggered aggregation in 22 of 44 PPP-PRP mixtures, with a median aggregation of 86% (interquartile range [IQR], 69-91). The median aggregation of these 22 positive samples' respective control tests was 22% (IQR, 16-3 (P 95% in 10 of the 22 positive samples (45%). Cangrelor inhibited heparin-induced aggregation by less then 50% in 5 of the 22 positive samples (22%) and by less then 10% in 3 samples (