https://www.selleckchem.com/pr....oducts/nms-p937-nms1
s did not perform well when applied to real-world EHR data, retraining the models using real-world EHR data and optimizing variable selection was beneficial for model performance. As clinical evidence evolves to include more real-world data, both industry and academia will likely search for ways to balance model optimization with generalizability. This study provides a pragmatic approach to applying RCT-trained models to real-world data. In this study, although the RCT-trained models did not perform well when applied to real