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High androgen levels in PCOS can result in a decreased ability to use insulin (a condition known as insulin resistance) to take blood sugar into cells to use for energy. This can lead to increased fat storage, which in turn can increase androgens. We said earlier that anything that impacts the hypothalamus, pituitary gland, and adrenal glands can influence our testosterone production. Some of the leading causes of high testosterone levels in women are polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia (CAH), thyroid problems, and insulin resis

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Sumanirole restored behavioural alterations as measured by rotarod performance, grip strength, adhesive tape removal analysis and neurological deficits. In addition, it also refurbished mitochondrial dysfunction by decreasing mitochondrial reactive oxygen species production, elevating mitochondrial membrane potential and by protecting the activity of mitochondrial complexes along with histological alterations. As a result, infarct sizes were markedly reduced in tMCAO surgery animals. Findings from the study provide evidence that SUM pro