https://www.selleckchem.com/pr....oducts/trc051384.htm
We also analyzed statistics on adducts from spectra contained in the three selected mass spectral libraries. MSAC is freely available at https//github.com/pnnl/MSAC.Naegleria fowleri is the protozoan pathogen that causes primary amoebic meningoencephalitis (PAM), with the death rate exceeding 97%. The amoeba makes sterols and can be targeted by sterol biosynthesis inhibitors. Here, we characterized N. fowleri sterol 14-demethylase, including catalytic properties and inhibition by clinical antifungal drugs and experimental substituted
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