https://www.selleckchem.com/pr....oducts/amlexanox.htm
Maturity-onset diabetes of the young (MODY) 8 is a rare form of monogenic diabetes characterized by a mutation in CEL (carboxyl ester lipase) gene, which leads to exocrine pancreas dysfunction, followed by β cell failure. Induced pluripotent stem cells can differentiate into functional β cells. Thus, β cells from MODY8 patients can be generated in vitro and used for disease modelling and cell replacement therapy. A genetic study was performed in a patient suspected of monogenic diabetes. A novel heterozygous pathogenic variant in CEL
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