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We propose that patients and primary care physicians should consider a cumulative SCS dose of 1 g per year as a highly relevant and easy-to-recall threshold. Copyright ©ERS 2020.OBJECTIVE To describe the pathological features of Guillain-Barré syndrome focusing on macrophage-associated myelin lesions. METHODS Longitudinal sections of sural nerve biopsy specimens from 11 patients with acute inflammatory demyelinating polyneuropathy (AIDP) exhibiting macrophage-associated demyelinating lesions were examined using electron microscopy. A total