https://www.selleckchem.com/pr....oducts/nutlin-3a.htm
OBJECTIVE The aim of this study to evaluate histopathological improvement and virological, serological and biochemical response rates in patients with chronic hepatitis B (CH who were treated with tenofovir disoproxil fumarate (TDF). MATERIAL AND METHOD A total of 91 nucleosid(t)e-naive CHB patients who received TDF were evaluated. Virological, serological and biochemical test results were assessed at baseline and every 12 weeks. Liver biopsy specimens were assessed according to the modified Ishak scoring. RESULTS The study was cond