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They can still generate grades of recommendation even when the evidence is inconclusive. © 2020 John Wiley Sons A/S. Published by John Wiley Sons Ltd.Autoimmune liver diseases (AILD), namely autoimmune hepatitis (AIH), primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), are rare diseases. These days, patients with PBC almost never require liver transplantation. When treated early with ursodeoxycholic acid patients have a normal life expectancy if the disease is diagnosed at an early stage and the pati