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professional. The research was funded by a grant from the Wellcome Trust (110126/Z/15/Z) to KEK. The Cat 3 facilities were made possible by an award from the BBSRC (BB/T00083X/1) to Jennifer Cavet. The research was funded by a grant from the Wellcome Trust (110126/Z/15/Z) to KEK. The Cat 3 facilities were made possible by an award from the BBSRC (BB/T00083X/1) to Jennifer Cavet.The ongoing SARS-CoV-2 pandemic is the third zoonotic coronavirus identified in the last twenty years. Previously, four other known coronaviruses moved from animal