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4; 95% confidence interval 4.95-14.17 and odds ratio 4.4; 95% confidence interval 2.36-9.39, respectively).Conclusion Rotterdam and Marshall CT scores have independent prognostic values in patients with TBI even in alcoholic patients. Prostate cancer is one of the most common neoplasms in men. For many years the mainstay of treatment was androgen deprivation therapy, but during last decade many novel agents have emerged, accompanied by increased costs for healthcare systems. In this literature review, the authors provide a pharmacoeconom