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Treatments For ADHD in Adults The same treatments that work for children can also help adults manage their ADHD symptoms. They include medicine, therapy and a variety of coaching and coping techniques. Methylphenidate is the most common medication used to treat adult ADHD. The MPH class of medicines is effective by enhancing the activity in specific brain regions that control the behavior and attention. Stimulant Medication Stimulant medication is the foundation of treatment