https://www.selleckchem.com/pr....oducts/doxycycline.h
The aetiology and pathogenesis of vulvar lichen sclerosus (LS), a chronic inflammatory disease, is not completely clear. It has been found that local cellular immune abnormalities play an important role in the immune mechanism of LS, mainly characterised by abnormal numbers of Langerhans cells in the epidermis and abnormal numbers of dermal T lymphocytes. To evaluate the densities of Langerhans cells and T-lymphocyte subpopulations in vulvar LS. The density of Langerhans cells in the epidermis, and CD3 , CD4 and CD8 T cells in the d