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Thus, catalpol attenuates depressive-like behavior in pathological hyperglycemic state, and the antidepressant mechanism could at least be partly attributed to the upregulation of the PI3K/AKT/Nrf2/HO-1 signaling pathway in both brain regions, thus restoring the balance between oxidative and antioxidant damage. These data expanded the scientific understanding of catalpol and provided preclinical experimental evidence for its application.Recent studies have emphasized that adult hippocampal neurogenesis impairment may be associated with
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Travel Trek offers an exclusive and luxury Europe tour package designed to make your holidays unforgettable. This exciting package includes visits to Europe’s most iconic destinations, featuring enchanting cities like Paris, Rome, and Vienna, alongside breathtaking natural landscapes like the Swiss Alps and the Amalfi Coast. Enjoy premium accommodations, first-class travel arrangements, and curated experiences that immerse you in Europe’s rich culture, history, and cuisine. With expert-guided tours and personalized services, Travel Trek ensures every moment of your journey is filled with excitement and comfort. Just book this package and let Travel Trek handle the rest while you relax, explore, and create cherished memories on your dream European holiday.
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