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Correlation analysis indicated that these differential genes were strongly correlated. Conclusion These results suggest that chronic stress might induce depressive behaviors by disturbing the glutamine-glutamate-GABA cycle in the striatum, hippocampus, and cerebellum, and that the glutamine-glutamate-GABA cycle among these three brain regions might generate cooperative action in response to chronic stress. © 2020 Xu et al.Purpose This study aimed to assess the serum levels of intracellular adhesion molecule (sICAM-1), and vascular cell adh

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6 and 8 percentage points, respectively, to experience an improvement relative to those who were not incentivized. Meaningful improvements were observed for depression and pain PROMIS domains for subjects randomized to the incentive groups, presumably through their interaction with a PCP and the health care system. This finding was robust for the full sample and a group that reported more severe symptoms at baseline. Meaningful improvements were observed for depression and pain PROMIS domains for subjects randomized to the incentive g