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Ala307Thr and p.Asn680Ser. It has been shown that the polymorphisms of the gene affect the hormone response in the ovaries. Our data demonstrated that the FSHR mutations frequencies were higher in the patients with PCOS rather than control people significantly. These data showed that the polymorphisms of were significantly associated with PCOS in Iranian infertile women. Further studies with larger sample sizes are needed to be performed for explore the strength of the association. These data showed that the polymorphisms of FSHR were s