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Why Buy a Category B+ Driving License? If you need to drive a car and trailer that weighs over 26,000 pounds, you will need a class B license. It is possible to add an endorsement the CDL class you already have by taking a new knowledge and skills test. Passing an exam in category C1+E will upgrade your license to include the full B+E entitlement. (Subject to the maximum weight limit for your B licence.) This is only valid for UK drivers. Passenger Endorsements If you want to operate one vehicle that c

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New technologies such as multiplex immunohistochemistry and high plex in situ profiling may offer more insights into the sarcoma microenvironment. To date, clinical trials using immune checkpoint inhibitor monotherapy have not shown compelling clinical benefits. Combination therapy with dual checkpoint inhibitors or in combinations with other agents has yielded more promising results in dedifferentiated liposarcoma, undifferentiated pleomorphic sarcoma, angiosarcoma and alveolar soft-part sarcoma. Better understanding of the sarcoma imm