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001), and the combined positive cases of the experimental parturients had notably higher serum BPA and resistin levels ( 0.001). The incidence of fetal growth restriction, premature delivery and placental abruption of experimental group were higher than those of control group (P 0.05). There was no stillbirth in both groups. The positive expression of ACL with β2-GP1 is the culprit of adverse pregnancy, and the combined diagnosis can greatly improve the clinical screening rate of adverse pregnancy and provide more evidence fo