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Nevertheless, the impact of instinct bacteria on Pb absorption, bioaccumulation, and removal is essentially unknown. In this study, we use a mouse model to investigate the relationship between instinct microbiota, Pb-intolerant intestinal microbes and Pb poisoning. Very first, mice had been treated with a broad-spectrum antibiotic beverage to deplete their instinct microbiota, and were then acutely and orally subjected to Pb at 1304 mg/kg for 3 days .
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