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Boron-rich particles with the boron fraction ca.10-20 wt-% of controllable shape and size that can be easily prepared via simple ion co-assembly are promising material for tumor treatment by boron neutron capture therapy. Electroneutral, dynamic core-shell polymeric nanoparticles were prepared by co-assembly of cationic PEO- block -PGEA diblock copolymer with sodium closo -dodecaborate, Na 2 [B 12 H 12 ]. This is the first example of polymer nanoparticles based on [B 12 H 12 ] 2- nano-ion pairing. The high [B 12 H 12 ] 2- loading is pro