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According to the results, there was no change in the contents of IL-1β and cortisol in the saliva of subjects with occupational fatigue before and after fatigue, whereas, there was a significant change in the content of CgA before and after fatigue. However, there was no correlation between the content of CgA and fatigue. The results of the present study revealed that IL-1β, cortisol and CgA indicators are not suitable diagnostic markers for occupational fatigue.Low expression levels of 25-hydroxyvitamin D (vitamin D3) in the blood have