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We unearthed that the management of hAECs or hAEC-CM decreased liver damage and fibrosis, sustained hepatocyte proliferation, and paid down LPC numbers during persistent liver damage. Also, we undertook in vitro scientific studies to document both the cell-cell and paracrine-mediated results of hAECs on LPCs by investigating the effects of co-culturing the LPCs and hAECs and hAEC-CM on LPCs. We found small improvement in LPCs co-cultured with hAECs. In comparison, hAEC-CM enhances LPC prolif
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