https://www.selleckchem.com/pr....oducts/pf-04957325.h
take advantage of CD8+ cytotoxic T lymphocytes (CTLs). Here, we identified 22 HLA-A*2402-restricted CTL candidate epitopes derived from the nonstructural polyprotein 1a (pp1a) of SARS-CoV-2. We focused on pp1a and HLA-A*2402 because pp1a is conserved and HLA-A*2402 is predominant in East Asians. The conservation analysis revealed that the amino acid sequences of 7 out of the 22 epitopes were hardly affected by mutations in the database of SARS-CoV-2 variants. The information might be useful for designing the next-generation COVID-19
Like
Comment
Share
