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Hyaluronic acid (HA) filler reactions have been increasingly observed in recent years. Our study investigates whether the increased number of filler reactions observed since 2014 is associated with a specific histopathologic inflammatory pattern and type of filler. The institution's dermatopathology electronic database was retrospectively searched for histopathologic reactions to HA from January 2014 to December 2019. The age, sex, type of filler, procedure, location, and histopathologic patterns were recorded. From 2014 to 2019, there