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Colonic polyps occur in 30-40% of acromegalic patients, increasing the risk of colon carcinoma. Although debated, there is emerging evidence that metformin may play a protective role in diabetic and non-diabetic patients with colonic polyps and its use in chemoprevention is currently explored. Evaluate the prevalence of colonic polyps in acromegalic patients treated or not with metformin and explore its possible protective role. Exploratory cross-sectional study in two tertiary Italian referral centres. hods Out of 153 acromegalic patien
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