Mesothelioma Settlements Most mesothelioma lawsuits end in settlements rather than a jury verdict. In negotiations, defendants take into consideration a variety of factors, including the cost of treatment and lost income. Compensation from a mesothelioma lawsuit can assist a victim and their family. Lawsuits also hold those responsible for asbestos exposure accountable. The average settlement for mesothelioma is approximately $1 million. Compensation for Pain and Suffering Compensation may be available to mesothelioma patients or their family